首页> 外国专利> Method for detecting NAFLD or NASH or predicting risk, diagnostic kit for detecting NAFLD or NASH, method for determining the progress of liver fibrosis in a subject, and diagnosis for determining the progress of liver fibrosis in a subject Medicine kit

Method for detecting NAFLD or NASH or predicting risk, diagnostic kit for detecting NAFLD or NASH, method for determining the progress of liver fibrosis in a subject, and diagnosis for determining the progress of liver fibrosis in a subject Medicine kit

机译:用于检测NAFLD或NASH或预测风险的方法,用于检测NAFLD或NASH的诊断试剂盒,用于确定受试者的肝纤维化进展的方法以及用于确定受试者的肝纤维化进展的诊断

摘要

[PROBLEMS] To provide a new NAFLD and NASH diagnostic method that can be implemented more simply and does not place a burden on patients and medical staff, and subjects that may suffer from NAFLD and NASH It is an object of the present invention to provide a new method for determining the degree of liver fibrosis that does not place a burden on patients and medical workers. A total amount of carnitine, which is the total amount of free carnitine and total amount of acylcarnitine in a biological sample, is measured, and the total amount of acylcarnitine is measured by subtracting the amount of free carnitine from the total amount of carnitine. By comparing the measurement result with the reference value, early diagnosis of NAFLD and NASH and determination of the degree of liver fibrosis can be made. [Selection figure] None
机译:[问题]提供一种新的NAFLD和NASH诊断方法,该方法可以更简单地实施并且不会给患者和医护人员以及可能遭受NAFLD和NASH困扰的受试者带来负担。本发明的目的是提供一种新的NAFLD和NASH诊断方法。确定肝脏纤维化程度的新方法,不会给患者和医务人员带来负担。测定生物样品中游离肉碱的总量和酰基肉碱的总量,即肉碱的总量,并通过从肉碱总量中减去游离肉碱的量来测定酰基肉碱的总量。通过将测量结果与参考值进行比较,可以早期诊断NAFLD和NASH并确定肝纤维化程度。 [选择图]无

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