Method of detecting the contribution of interfering substances in a biosensor

摘要

Disclosed is a method of detecting a contribution by an interferent in a biosensor. In the present disclosure, the biosensor has a first electrode 112, a second electrode, and a third electrode 114, and the first electrode 112 and the second electrode are coated with a membrane, and the first electrode 112 is an enzyme. Further included or the first electrode 112 is coated with an enzyme layer. Further, the first electrode 112, the second electrode, and the third electrode 114 are connected via a potentiostat, and in the normal operation mode, the first electrode 112 enables an oxidation process, and the third electrode 114 is reduced. A potential difference is applied between the first electrode 112 and the second electrode via the potentiostat to enable the process. The method comprises the steps of: a) switching from the normal operating mode to the interfering substance detection mode, wherein in the interfering substance detection mode, the potential difference between the first electrode 112 and the second electrode causes the third electrode 114 to oxidize. To enable, changing in a limited period, b) measuring the current-voltage characteristic 110 of the third electrode 114, and c) evaluating the current-voltage characteristic 110 of the third electrode 114 Determining the contribution by interfering substances in the biosensor. This method makes it possible to deduct in the obvious way the presence of an interfering substance, preferably the amount of interfering substance, and is generally applicable in the case of more than one interfering substance. No additional working electrodes or auxiliary circuit components are required. This method can be implemented within standard biosensor sensor electronics structures and is thus applicable to existing biosensor systems.