Complexes of lumacafitol and its salts and derivatives, processes for their preparation and pharmaceutical compositions containing them

摘要

The present invention relates to a complex of lumacafitol (lumacuffol) or a salt thereof, and a pharmaceutically acceptable complex preparation comprising a complexing agent and a pharmaceutically acceptable excipient, a method for producing the same, and The present invention relates to a pharmaceutical composition contained. The complex formulations of the invention have improved dissolution and permeability in fasted and fed state simulations that are expected to result in complete absorption and elimination of food effects.