Generation of human macrophages in an immunodeficient non-human host

摘要

The present invention relates to the use of non-anti-human antibodies that stimulate the production of human macrophages in an immunodeficient non-human host reconstituted with a human immune system. Also included are such production methods and host models using human xenografts, and their use for the evaluation of cancer immunotherapies. [Selected figure] Figure 4