Composition for diagnosing thyroid cystic cancer using aminoacyl-tRNA synthetase-related protein expression level and diagnostic marker detection method

摘要

The present invention relates to a method for detecting a marker for diagnosis of thyroid follicular cancer using an aminoacyl-tRNA synthetase-related protein expression level, and more specifically, from a patient suspected of follicular thyroid carcinoma. (A) providing a sample from a subject suspected of having thyroid follicular cancer; (b) aminoacyl tRNA synthetase or aminoacyl tRNA synthetase complex from the sample to provide information necessary for diagnosis of cystic cancer; Measuring the protein expression level of the body-interacting multifunctional protein; and (c) comparing the measured protein expression level with the control group, The present invention relates to a method for detecting a marker for thyroid follicular cancer, comprising the step of determining that the cancer has developed. Specifically, the types of proteins disclosed in the present invention enable simple and clear diagnosis of thyroid follicular cancer without collecting tissues through surgery, and have high diagnostic sensitivity and specificity.