Thermal convection generation system and convection PCR method

摘要

[Problem] To provide a heat-convection-generating device and heat-convection-generating system having high reproducibility of heat convection and robustness superior to that of the prior art, whereby heat convection such as thermal cycling in PCR, for example, can be rapidly performed with good efficiency. [Solution] A heat convection generation chip 10, a shaft 41 capable of rotatably fixing the heat convection generation chip 10, first and second heaters 31, 32 having first and second heat source parts 31b, 32b for heating or cooling a liquid in an annular flow channel 14, and a motor 40 for rotating the shaft 41 and thereby causing the entire annular flow channel 14 to rotate about an axis AX of the shaft 41 are provided, and in plan view of the annular flow channel 14 in the direction orthogonal to the direction in which the liquid flows through the annular flow channel 14, the center of gravity (center of the annular flow channel) Q of the annular flow channel 14 in the plane and the center of rotation of the shaft 41 which is the point of intersection of the axis AX and the plane do not coincide, at least one heat source part 32b of the second heater 32 is positioned in only one range among the ranges of 30° to 150° or 210° to 330° about the center of gravity (center of the annular flow channel) Q with respect to a straight line Z connecting the center of rotation and the center of gravity (center of the annular flow channel) Q, and heats or cools a flow channel area of the annular flow channel 14 in the one range, and the first heater 31 heats or cools a flow channel area other than the flow channel area of the annular flow channel 14 heated or cooled by the second heater 32.