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Identify the IN in vitro methods of the movable modulator of neuromuscular junction

机译:鉴定神经肌肉接头活动调节剂的体外方法

摘要

The present invention relates to the neuromuscular junction models of integrated stranger, prepare from the co-incubation of Skeletal Muscle Cell derived from versatile stem cell (PSC)-motorneuron of derivative spine and the sarcoblast of people. The present invention is also being provided by a kind of method for determining whether that candidate compound increases or decreases the screening compounds of the activity modulation movable ability of neuromuscular junction of the neuromuscular junction model of external people for them.
机译:本发明涉及整合的陌生人的神经肌肉连接模型,其是通过衍生自衍生脊柱的多功能干细胞(PSC)-运动神经元和人的成骨细胞的骨骼肌细胞的共孵育而制备的。本发明还通过一种用于确定候选化合物是增加还是减少外部人的神经肌肉接头模型的神经肌肉接头的活性调节活动能力的筛选化合物的方法来提供。

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