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METHODS FOR DETECTING CPG METHYLATION OF TUMOR-DERIVED DNA IN BLOOD SAMPLES

机译:检测血液样本中肿瘤来源DNA的CPG甲基化的方法

摘要

The present invention relates to the field of pharmacogenomics and in particular to detecting the presence or absence of methylated ANKRD13B and/or FOXF2 DNA derived from a tumor in blood or blood-derived samples or in other body fluids that contain DNA released from a tumor. This detection is useful for a minimally invasive diagnosis of cancers and the invention provides methods and oligonucleotides suitable for this purpose.
机译:本发明涉及药物基因组学领域,尤其涉及检测血液或血液来源的样品或含有从肿瘤释放的DNA的其他体液中是否存在源自肿瘤的甲基化的ANKRD13B和/或FOXF2 DNA。该检测对于癌症的微创诊断是有用的,并且本发明提供了适合于该目的的方法和寡核苷酸。

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