Use of stilipentol and its derivatives to reduce urinary oxalate concentrations in individuals

摘要

The present invention provides a compound of formula (I) for use in reducing urinary oxalate concentration in an individual: (wherein -n is 1 or 2, -Z1, Z2 and Z3 are May be the same or different and is selected from a hydrogen atom, a halogen atom, and a (C1-C6) alkyl group, -R is substituted with one or more substituents selected from a hydroxyl group, an oxo group, and a thiol group (Which is a C1-C6) alkyl group) or one of its pharmaceutically acceptable salts. The present invention further relates to compounds for use in the prevention and / or treatment of diseases and / or conditions associated with high urinary oxalate concentrations in individuals.