A novel anti-human transferrin receptor antibody that crosses the blood-brain barrier

摘要

The present invention relates to an anti-human transferrin receptor antibody, wherein the antibody comprises (a) CDR1 comprising the amino acid sequence of SEQ ID NO: 62 or SEQ ID NO: 63 in the variable region of the heavy chain; Provided are antibodies and analogs thereof comprising the amino acid sequence of SEQ ID NO: 13 or SEQ ID NO: 14 and (c) CDR3 comprising the amino acid sequence of SEQ ID NO: 15 or SEQ ID NO: 16.