METHODS FOR MASS SPECTROMETRY-BASED STRUCTURE DETERMINATION OF BIOMACROMOLECULES

摘要

The invention provides methods and tools for determining the structure of biomacromolecules such as proteins in a sample using mass spectrometry. More particularly the methods allow determining the presence of a biomacromolecule of an organism in a sample by comparing an observed mass spectrum of the sample with a theoretical fragment ion spectrum comprising theoretical fragment ion masses.