首页> 外国专利> Resorbable cross-linked shape-stabilizing membrane

Resorbable cross-linked shape-stabilizing membrane

机译:可吸收的交联形状稳定膜

摘要

The invention relates to: - A resorbable crosslinked form stable membrane which comprises a composite layer of collagen material and inorganic ceramic particles containing 1.5 to 3.5 weight parts of inorganic ceramic for 1 weight part of collagen material, sandwiched between two layers of elastic pretensed collagen material, the collagen material comprising 50-100 % (w/w) collagen and 0-50 % (w/w) elastin, - the above crosslinked resorbable crosslinked form stable membrane for use as an implant to support bone formation, bone regeneration, bone repair and/or bone replacement at a non-containing dental bony defect site in a human or animal, - a process for preparing the above crosslinked resorbable crosslinked form stable membrane comprising the steps of: (a) Preparing a composite layer of inorganic ceramic particles and collagen material, optionally crosslinking that composite layer, (b) Assembling and glueing the composite layer of collagen material and inorganic ceramic particles between two layers of collagen material submitted to tensioning leading to a stretching of the collagen material in the linear region of the stress-strain curve, thereby giving a composite layer of collagen material and inorganic ceramic particles sandwiched between two layers of elastic pretensed collagen material, and (c) Crosslinking that composite layer of collagen material and inorganic ceramic particles sandwiched between two layers of elastic pretensed collagen material, followed by a hydrophilic making treatment.
机译:本发明涉及:-可吸收的交联形式稳定的膜,其包含胶原材料和无机陶瓷颗粒的复合层,所述无机陶瓷颗粒包含相对于1重量份胶原材料为1.5-3.5重量份的无机陶瓷,其夹在两层弹性拉伸的胶原材料之间,所述胶原材料包括50-100%(w / w)胶原蛋白和0-50%(w / w)弹性蛋白,-上述交联的可吸收的交联形式稳定的膜,用作在人或动物的不含骨的骨缺损部位中支持骨形成,骨再生,骨修复和/或骨置换的植入物,-制备上述交联的可吸收的交联形式稳定的膜的方法,包括以下步骤:(a)准备无机​​陶瓷颗粒和胶原材料的复合层,可选地使该复合层交联,(b)将胶原材料和无机陶瓷颗粒的复合层组装并粘合在两层胶原材料之间,使其经受拉紧作用,导致胶原材料在应力-应变曲线的线性区域中拉伸,从而得到复合材料层。胶原材料和无机陶瓷颗粒夹在两层弹性拉伸的胶原材料之间,以及(c)使胶原材料和无机陶瓷颗粒的复合层夹在两层弹性拉伸的胶原材料之间交联,然后进行亲水性处理。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号