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Method for detecting hemolysis of blood sample and chip for hemolysis detection

机译:血样溶血的检测方法及溶血检测用芯片

摘要

A novel method of sensitively detecting hemolysis of a blood sample is disclosed. In the hemolytic detection method according to the present invention, the presence or absence of hemolysis is detected by using at least one type of miRNA whose abundance increases in hemolyzed blood samples as a hemolytic marker and using the abundance as an indicator to evaluate the presence or absence of hemolysis Do. According to the method of the present invention, hemolysis can be detected with high sensitivity even in a blood sample in which the degree of hemolysis is small and the outflow of red blood cell contents such as hemoglobin is small.
机译:公开了灵敏地检测血液样品的溶血的新方法。在根据本发明的溶血检测方法中,通过使用至少一种类型的miRNA检测溶血的存在或不存在溶血,所述miRNA的溶血血样中的丰度增加作为溶血标记,并使用所述丰度作为指示物来评估是否存在溶血或溶血。没有溶血吗。根据本发明的方法,即使在溶血度小且血红蛋白等红细胞成分的流出少的血液样本中,也可以高灵敏度检测溶血。

著录项

  • 公开/公告号JPWO2018056432A1

    专利类型

  • 公开/公告日2019-07-04

    原文格式PDF

  • 申请/专利权人 東レ株式会社;

    申请/专利号JP20170550662

  • 发明设计人 名取 一恵;近藤 哲司;

    申请日2017-09-25

  • 分类号C12N15/09;G01N33/50;G01N33/53;G01N37;C12Q1/68;C12M1;C12M1/34;

  • 国家 JP

  • 入库时间 2022-08-21 12:18:25

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