Substituted 4,5,6,7-tetrahydro-pyrazolo 1,5-a pyrimidine derivatives as ROS1 inhibitors and 2,3-dihydro-1H-imidazo 1,2-b pyrazole derivatives

摘要

wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as ROS1 inhibitors. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.