Agents for ion transcellular transporters in the intestinal tract, chloride channel activators, preventive or therapeutic agents for renal diseases, or defecation promoters

摘要

Provide an agent for intestinal ionic transcellular transporter containing a bacterium belonging to the genus Bifidobacterium or Lactobacillus or a processed product thereof (however, the ion transporter is a chloride channel) When the action is inhibition, the ion transporter is Na + K + Cl− cotransporter (NKCC1), and when the action is inhibition, the bacterium is Bifidobacterium infantis 35624 (Bifidobacterium infantis 35624) And the bacterium is Lactobacillus salivarius UCC118). The agent of the present invention is useful for activating chloride channels, preventing or treating renal diseases, and / or promoting defecation, and can be used as a medicine, supplement, and the like.