Biocompatible long-fiber non-woven fabric, method for producing the same, three-dimensional scaffold for cell culture and cell culture method using the same

摘要

The present invention is a biocompatible long-fiber non-woven fabric comprising a biocompatible polymer as a main component, wherein the biocompatible long-fiber constituting the biocompatible long-fiber non-woven fabric has a change in fiber diameter in the length direction and a fiber intersection point The present invention relates to a biocompatible long-fiber non-woven fabric which is at least partially welded, does not get wet when it gets wet, and becomes transparent when it gets wet. The biocompatible long-fiber non-woven fabric pushes a spinning solution containing a biocompatible polymer into the air from the nozzle discharge port 3 and is positioned behind the nozzle discharge port 3 and does not contact the nozzle discharge port 3. The pressure fluid 7 is jetted from the front toward the front, and the extruded spinning solution is caused to accompany the pressure fluid 7 to form fibers, and the long fibers 8 having the fibers formed are accumulated to produce a long fiber non-woven fabric 9 be able to. This provides a biocompatible long-fiber non-woven fabric having high moldability and molding stability useful for medical applications and scaffolds for cell culture, a method for producing the same, a three-dimensional scaffold for cell culture, and a cell culture method using the same.