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Methods to inhibit infection during wound healing with topical compositions including amino acids

机译:用包括氨基酸的局部组合物在伤口愈合过程中抑制感染的方法

摘要

A method that inhibits infection during wound healing by topical application of a single composition, which contacts a wound for a period of time to initiate wound healing. The single composition may include a mixture of all or some of the amino acids including: histidine monohydrochloride monohydrate; isoleucine; leucine; lysine acetate; methionine; phenylalanine; threonine; tryptophan; valine; alanine; arginine acetate; aspartic acid; glutamine; glycine; proline; serine; and tyrosine, which may provide aqueous mixtures of a range of osmolarities or a powdered mixture of amino acids. The single composition may also include any of a carbohydrate, a mixture of fatty acids, vitamins, and mineral nutrients, and another mixture of amino acid derivatives and preservatives. The number of moles of the carbohydrate is less than and proportional to a sum of the number of moles of any mixture of amino acids in the single composition.
机译:一种通过局部施用单一组合物抑制伤口愈合期间感染的方法,该单一组合物接触伤口一段时间以启动伤口愈合。该单一组合物可以包括全部或一些氨基酸的混合物,包括:组氨酸一盐酸盐一水合物;和异亮氨酸亮氨酸醋酸赖氨酸;蛋氨酸苯丙氨酸苏氨酸色氨酸缬氨酸丙氨酸乙酸精氨酸天冬氨酸;谷氨酰胺甘氨酸脯氨酸丝氨酸酪氨酸和酪氨酸,它们可以提供各种渗透压的水性混合物或氨基酸的粉末混合物。单一组合物还可包含任何碳水化合物,脂肪酸,维生素和矿物质营养素的混合物以及氨基酸衍生物和防腐剂的另一种混合物。碳水化合物的摩尔数小于和与单一组合物中氨基酸的任何混合物的摩尔数之和成正比。

著录项

  • 公开/公告号US10413528B2

    专利类型

  • 公开/公告日2019-09-17

    原文格式PDF

  • 申请/专利权人 JOHN H. PLUMB;

    申请/专利号US201414518449

  • 发明设计人 JOHN H. PLUMB;

    申请日2014-10-20

  • 分类号A61K31/4172;A61K31/198;A61K31/405;A61K31/401;A61K31/716;A61K31/202;A61K31/07;A61K31/593;A61K31/355;A61K31/195;A61K33/30;

  • 国家 US

  • 入库时间 2022-08-21 12:17:06

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