首页>
外国专利>
Treatment of Rb-negative tumors using topoisomerase with cyclin dependent kinase 4/6 inhibitors
Treatment of Rb-negative tumors using topoisomerase with cyclin dependent kinase 4/6 inhibitors
展开▼
机译:使用拓扑异构酶和细胞周期蛋白依赖性激酶4/6抑制剂治疗Rb阴性肿瘤
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention is in the area of improved therapeutic combinations for and methods of treating selected retinoblastoma (Rb)-negative cancers and Rb-negative abnormal cellular proliferative disorders using particular topoisomerase inhibitors and specific cyclin-dependent kinase 4/6 (CDK4/6) inhibitors. In one aspect, the improved treatment of select Rb-negative cancers is disclosed using specific compounds disclosed herein in combination with a topoisomerase I inhibitor.
展开▼