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Selective capture and stimulated release of circulating tumor cells on nanostructured devices
Selective capture and stimulated release of circulating tumor cells on nanostructured devices
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机译:在纳米结构装置上选择性捕获和刺激循环肿瘤细胞的释放
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摘要
A device for capturing preselected cell types from a fluid sample that includes a plurality of cell types includes a substrate, a plurality of nanowires at least one of attached to or integral with a surface of the substrate such that each nanowire of the plurality of nanowires has an unattached end, and a layer of temperature-responsive material formed on at least the unattached end of each of the plurality of nanowires. The layer of temperature-responsive material has a compact configuration at a first temperature and an expanded configuration at a second temperature so as to facilitate release of cells captured at the first temperature to be released at the second temperature.
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