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Pharmaceutical compositions to reduce complications of ocular steroid

机译:减少眼类固醇并发症的药物组合物

摘要

The present invention relates to pharmaceutical compositions comprising a combination of a lipid cake mixture comprising one or more phospholipids, with or without cholesterol, and a steroid solution comprising an ocular steroid, derivative thereof, a pharmaceutically acceptable salt thereof or a prodrug thereof, wherein the total amount of the phospholipid in the said composition is about 0.1 umol to less than about 2.5 umol per 50 ul of pharmaceutical composition and the side effects of the ocular steroid are reduced. The pharmaceutical composition is preferably administered by ocular route to treat ophthalmic diseases.
机译:本发明涉及药物组合物,所述药物组合物包含脂质饼混合物和甾类溶液的组合,所述脂质饼混合物包含一种或多种磷脂,所述胆固醇具有或不具有胆固醇,所述甾类溶液包含眼类固醇,其衍生物,其药学上可接受的盐或其前药。所述组合物中磷脂的总量为每50ul药物组合物约0.1umol至小于约2.5umol,并且降低了眼类固醇的副作用。药物组合物优选通过眼途径给药以治疗眼科疾病。

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