High-speed tissue oximetry system employing fast digital diffuse optical spectroscopy

摘要

A tissue oximetry system employing diffuse optical spectroscopy includes an optical subsystem and an electronics and processing subsystem, together generating modulated optical signals processing a response optical signal in order to obtain measurements of blood oxygen values for a tissue from per-wavelength absorption values. Signal sources generate RF modulation signals, and ADC circuitry generates streams of digital sample values from analog detection signals. Data acquisition circuitry and a processor (1) provide RF modulation command values in synchronism with sampling operation according to an offset pattern and rate, stepping through an RF range to obtain measurements of the absorption values in measurement intervals at least 10 times per second, (2) in each of the measurement intervals, calculate the model to obtain the blood oxygen values from the measurements of the absorption values, and display or otherwise use the obtained blood oxygen values in higher-level diagnostic assessment of tissue blood oxygenation.