Peptide inhibitors of serotonin 5-HT_2C receptor:PTEN interaction

摘要

The inventors have identified how the assembly of the 5-HT2cR with another protein (phosphatase and tensin homologue; PTEN) controls cellular function, and have synthesized a new peptide that interrupts the 5-HT2cR:PTEN complex to result in enhanced 5-HT2cR function.