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Microsphere-based delivery and ex vivo manipulation of dendritic cells for autoimmune therapies
Microsphere-based delivery and ex vivo manipulation of dendritic cells for autoimmune therapies
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机译:基于微球的树突状细胞递送和离体操作,用于自身免疫治疗
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摘要
The present invention relates to tolerogenic mammalian dendritic cells (iDCs) and methods for the production of tolerogenic DCs. In addition, the present invention provides methods for administration of tolerogenic dendritic cells as well as particles containing oligonucleotides to mammalian subjects. Enhanced tolerogenicity in a host can be useful for treating inflammatory and autoimmune related diseases, such as type 1 diabetes.
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