PHARMACEUTICAL COMPOSITION OF (3-HYDROXY-4 -PYRON-2-YL) METHYL -AMINE DERIVATIVES AND DNA DEMETHYLATING AGENTS AND THEIR USE AS ANTI-NEOPLASTIC DRUGS

摘要

The present invention concerns pharmaceutical compositions comprising compounds with general formula I or poly-alkyl-bis-maltolic molecules and in particular derivatives of [(3-hydroxy-4-pyron-2-yl)methyl]-amine in combination with DNA demethylating agents as anti-neoplastic drugs. In particular, for the preparation of a medicament for the treatment of neoplastic pathologies.