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Polycation-Functionalized Nanoporous Silicon Carrier for Systemic Delivery of Gene Silencing Agents
Polycation-Functionalized Nanoporous Silicon Carrier for Systemic Delivery of Gene Silencing Agents
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机译:聚阳离子功能化的纳米多孔硅载体,用于系统地传递基因沉默剂。
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摘要
Disclosed are methods and compositions containing functionalized nanoporous silicon particles, useful in a variety of diagnostic and/or therapeutic regimens for delivery of genetic constructs to one or more cells, tissues, and/or organs of interest. Also provided are methods for introducing into selected host cells one or more selected nucleic acid molecules. The present disclosure is also directed to a method of treating a tumor, comprising the step of administering to an individual one or more of the compositions and formulations thereof as described herein.
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