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Low molecular polypeptide ZY4 and applications thereof

机译:低分子多肽ZY4及其应用

摘要

The present invention discloses the applications of a low molecular polypeptide ZY4 in preparing drugs for anti-acnes, anti-infection, anti-cancer and cosmetics. The low molecular polypeptide ZY4 comprises 17 amino acid residues, with a molecular weight of 2374.0 Da, an isoelectric point of 10.74, and an amino acid sequence of SEQ ID NO:1. The low molecular polypeptide ZY4 in the invention is artificially synthesized, with the advantages of small molecular weight and convenient artificial synthesis. The experiments have showed that the polypeptide ZY4 has obvious antibacterial effect and has significant therapeutic effect on acnes. The polypeptides can inhibit the growth of tumor cells and kill the tumor cells. The low molecular polypeptide ZY4 can be used in the preparation of medicaments or cosmetics having the effect of anti-infective, anti-tumor or anti-acne.
机译:本发明公开了低分子多肽ZY4在制备抗痤疮,抗感染,抗癌和美容药物中的应用。低分子多肽ZY4包含17个氨基酸残基,分子量为2374.0Da,等电点为10.74,并且氨基酸序列为SEQ ID NO:1。本发明的低分子多肽ZY4是人工合成的,具有分子量小,人工合成方便的优点。实验表明,ZY4多肽具有明显的抗菌作用,对痤疮具有显着的治疗作用。多肽可以抑制肿瘤细胞的生长并杀死肿瘤细胞。低分子多肽ZY4可用于制备具有抗感染,抗肿瘤或抗痤疮作用的药物或化妆品。

著录项

  • 公开/公告号US10208088B1

    专利类型

  • 公开/公告日2019-02-19

    原文格式PDF

  • 申请/专利权人 SICHUAN SYNLIGHT BIOTECH LTD.;

    申请/专利号US201615580694

  • 发明设计人 YANJUN DU;DAFU ZENG;

    申请日2016-01-12

  • 分类号A61K38/10;C07K7/08;A61P17/10;A61P35;A61P31/10;A61K47/10;A61P31/04;A61K38;

  • 国家 US

  • 入库时间 2022-08-21 12:12:46

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