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Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides

机译:截短的LYP-1肽以及使用截短的LYP-1肽的方法和组合物

摘要

Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences, such as truncated LyP-1 peptides, that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.
机译:公开了可用于将分子靶向和内在感兴趣细胞中以及可被感兴趣组织的分子穿透的组合物和方法。所述组合物和方法基于肽序列,例如截短的LyP-1肽,其被细胞选择性地内在化,穿透组织或两者。所公开的内化作用和组织渗透可用于将治疗剂和可检测剂递送至目的细胞和组织。

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