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Methods and systems for assessing infertility and related pathologies

机译:评估不孕症和相关疾病的方法和系统

摘要

Methods for assessing infertility and related pathologies and informing treatment type and timing thereof are provided. According to certain embodiments, methods of the invention include determining levels of one or more transcripts present in a sample obtained from a subject suspected of having endometriosis, identifying transcript levels that correspond to a regulation pattern specific to a time-point in a uterine cycle, and characterizing endometriosis of the subject based upon the identified transcript levels. The invention includes methods for assessing age-associated increase in aneuploidy rates based on FSH levels and IVF success rates based on obesity in PCOS patients.
机译:提供了用于评估不育症和相关病状并告知治疗类型和时间的方法。根据某些实施方案,本发明的方法包括确定从怀疑患有子宫内膜异位的受试者获得的样品中存在的一种或多种转录物的水平,鉴定与子宫周期中特定时间点的调控模式相对应的转录水平,并基于所确定的转录水平表征受试者的子宫内膜异位。本发明包括用于基于PCOS患者中的FSH水平和基于肥胖的IVF成功率评估与年龄相关的非整倍体率增加的方法。

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