METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NON SMALL CELL LUNG CANCER (NSCLC) THAT COEXISTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

摘要

The disclosure relates to methods and pharmaceutical compositions for the treatment of non-small cell lung cancer (NSCLC) that coexists with chronic obstructive pulmonary disease (COPD). In particular, the disclosure relates to a method of treating non-small cell lung cancer (NSCLC) in a patient suffering from chronic obstructive pulmonary disease (COPD) comprising administering to the patient a therapeutically effective amount of an immune checkpoint inhibitor such as is a multispecific antibody comprising at least one binding site that specifically binds to a PD-1 molecule and at least one binding site that specifically binds to a TIM-3 molecule.