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MICROFLUIDIC SYSTEM FOR SPERM SEPARATION AND ENRICHMENT FROM VARIOUS TYPES OF SPERM SAMPLES
MICROFLUIDIC SYSTEM FOR SPERM SEPARATION AND ENRICHMENT FROM VARIOUS TYPES OF SPERM SAMPLES
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机译:用于从各种类型的精子样品中分离和富集的微流控系统
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摘要
A method for separating and enriching sperm from a tissue sample comprises: obtaining a microfluidic separating system having an inlet end and an outlet end, and a membrane filter (e.g., hollow fiber membrane filter) fluidly connected to the outlet end; separating the tissue sample via the microfluidic separating system into a debris fluid volume and a sperm fluid volume; and enriching the sperm fluid volume by removing excess media via the membrane filter. A two-stage tissue sample separation system comprising: a microchannel structure defining a separation fluid channel to form a separation stage; an inlet end of the microchannel structure; an outlet end of the microchannel structure; and a membrane filter fluidly connected to the outlet end for removal of at least a portion of excess media in the tissue sample.
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