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METHODS OF TREATING NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS USING INTERLEUKIN-17 (IL-17) ANTAGONISTS

机译:白介素17(IL-17)拮抗剂治疗非放射学性轴突性脊椎关节炎的方法

摘要

The present disclosure relates to methods for treating non-radiographic axial spondyloarthritis (nr-axSpA) patients and inhibiting the progression of structural damage in these patients, using Interleukin-17 (IL-17) antagonists, e.g., secukinumab. Also disclosed herein are uses of IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab, for treating nr-axSpA patients and inhibiting the progression of structural damage in these patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
机译:本公开涉及使用白细胞介素17(IL-17)拮抗剂例如苏金单抗治疗非放射线轴性脊柱关节炎(nr-axSpA)患者并抑制这些患者中结构损伤的进展的方法。本文还公开了IL-17拮抗剂,例如IL-17抗体,例如secukinumab,用于治疗nr-axSpA患者并抑制这些患者中结构性损伤的进展,以及药物,给药方案,药物制剂,用于公开的用途和方法的剂型和试剂盒。

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