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Lactylates for the prevention and treatment of infections caused by gram-positive bacteria in animals
Lactylates for the prevention and treatment of infections caused by gram-positive bacteria in animals
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机译：乳酸酯用于预防和治疗动物中由革兰氏阳性细菌引起的感染
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摘要
The present invention pertains to the use for preventing or treating intestinal infections caused by gram-positive bacteria in animals of an antibacterial compound selected from lactylate in accordance with formula 1,; R2—COO—[—CH(CH3)—COO]n—R1 Formula 1 ;or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof, a glycolylate of formula 2,; R2—COO—[—CH2—COO]n—R1 Formula 2 ;or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof, a lactate ester of formula 3,; HO—CH(CH3)—COO—R2 Formula 3 ;and/or a glycolic acid ester of formula 4,; HO—CH2—COO—R2 Formula 4 ;wherein R1 is selected from H, n stands for an integer with a value of 1-10, and R2 stands for a C1-C35 alkyl or alkenyl chain which may be branched or unbranched.;The compound, which preferably is a lactylate or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof, is particularly useful in the treatment or prevention of Clostridia. An animal nutrition composition and a method for preventing or treating infections are also claimed.
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机译：本发明涉及用于预防或治疗由革兰氏阳性细菌在动物中引起的肠道感染的用途，所述动物选自式1的乳酸酯; <？in-line-formulae description =“在线公式” end =“ lead”？> R 2 -COO-[-CH（CH 3 ）-COO ] n -R 1 公式 1 <？in-line-formulae description =“ In-line Formulae” end =“ tail”？> ;或其Na，K，Ca，Mg，Fe（II），Zn，NH 4 或Cu（II）盐，式2的乙醇酸酯; <？in-line-formulae description =“在线公式” end =“ lead”？> R 2 -COO-[-CH 2 -COO] n —R 1 公式 2 <？in-line-formulae description =“ In-line Formulae” end =“ tail”？>;或Na，K，Ca，Mg，Fe（II），Zn，NH 4 或其Cu（II）盐，式3的乳酸酯， <？in-line-formulae description =“在线公式” end =“ lead”？> HO-CH（CH 3 ）-COO-R 2 公式< B> 3 <？in-line-formulae description =“ In-line Formulae” end =“ tail”？>;和/或式4的乙醇酸酯; <？in-line-formulae description =“在线公式” end =“ lead”？> HO-CH 2 -COO-R 2 公式 4 <？in-line-formulae description =“ In-line Formulae” end =“ tail”？;其中R1是从H中选择的，n表示值为1-10的整数，R2表示可以是支链或直链的C1-C35烷基或烯基链;该化合物，最好是乳酸酯或Na，K，Ca，Mg，Fe（II），Zn，NH 4 或其铜盐（II）在治疗或预防 C>梭状芽孢杆菌中特别有用。还要求保护动物营养组合物和预防或治疗感染的方法。
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