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MULTIMODAL PET/MRI CONTRAST AGENT AND A PROCESS FOR THE SYNTHESIS THEREOF
MULTIMODAL PET/MRI CONTRAST AGENT AND A PROCESS FOR THE SYNTHESIS THEREOF
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机译:多模态PET / MRI造影剂及其合成方法
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摘要
A multimodal PET (positron emission tomography)/MRI (magnetic resonance imaging) contrast agent, a process of synthesizing said PET/MRI contrast agent, and a pharmaceutical formulation comprising said PET/MRI contrast agent are disclosed. The PET/MRI contrast agent comprises a magnetic signal generating core, and a coating portion formed at least partially over a surface of said magnetic signal generating core, wherein the coating portion comprises a plurality of layers, including an inner layer having a functionalized surface, and an outer layer in the form of a radionuclide electrolessly plated layer formed on said functionalized surface.
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机译:公开了一种多峰PET(正电子发射断层摄影)/ MRI(磁共振成像)造影剂,所述PET / MRI造影剂的合成方法以及包含所述PET / MRI造影剂的药物制剂。 PET / MRI造影剂包括磁信号产生芯和至少部分地形成在所述磁信号产生芯的表面之上的涂层部分,其中涂层部分包括多层,包括具有功能化表面的内层,形成在所述功能化表面上的放射性核素化学镀层形式的外层。
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