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POLY(GLYCEROL SEBACATE)-INTERLEUKIN INHIBITOR COPOLYMERS AND METHODS OF MAKING AND USE
POLY(GLYCEROL SEBACATE)-INTERLEUKIN INHIBITOR COPOLYMERS AND METHODS OF MAKING AND USE
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机译:聚(癸二酸甘油酯)-白细胞介素抑制剂共聚物及其制备和使用方法
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摘要
A method includes combining an alcohol-pharmaceutical conjugate, a polyol, and an aqueous liquid in a vessel. The alcohol-pharmaceutical conjugate includes a pharmaceutical compound having at least one carboxyl group attached to the polyol by an ester bond. The method also includes adding an acid monomer to the vessel and heating and removing water from the vessel to produce the polymeric material. The polymeric material includes a polyester copolymer of the acid monomer and the polyol and the pharmaceutical compound.
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