首页>
外国专利>
MYO1A FOR PREDICTING CONVERSION OF ACUTE PAIN INTO CHRONIC PAIN AND USE OF MYO1A FOR THERAPY OF PAIN
MYO1A FOR PREDICTING CONVERSION OF ACUTE PAIN INTO CHRONIC PAIN AND USE OF MYO1A FOR THERAPY OF PAIN
展开▼
机译:MYO1A用于预测急性疼痛转化为慢性疼痛以及MYO1A在疼痛治疗中的用途
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to the identification of Myo1a as a biomarker of conversion of acute pain into chronic pain, and as a therapeutic target. The invention in particular relates to products and methods for assessing the predisposition of a subject to develop an injury-induced chronic mechanical pain and/or an inflammatory-induced chronic thermal pain, and is particularly suited for mammals, preferably human subjects. The present invention more specifically relates to the assessment of the predisposition of a subject to develop an injury-induced chronic mechanical pain and/or an inflammatory-induced chronic thermal pain using preferably the MYO1A gene as a biomarker. Inventors herein provide binding reagents specific for MYO1A, compositions, devices, kits containing the same and animal model, and further describe their uses for assessing the predisposition of a subject to suffer from chronic pain. The invention also relates to products and methods for diagnosing, preventing, managing or treating chronic pain.
展开▼