COMPOSITIONS FOR THE REMINERALIZATION OF DENTIN

摘要

Provided herein are novel compositions for the restoration of demineralized tissues, such as dentin which has been demineralized by tooth decay. The remineralization agent comprises a bioactive ceramic component and a polyanionic macromolecular component, which may be admixed and applied to the target tissue and which will subsequently set to produce a remineralizing solid. The remineralizing solid will produce nanodroplets of mineral precursor solution, which such nanodroplets can infiltrate demineralized collagen matrices and which will form hydroxyapatite crystals therein by polymer-induced liquid precursor processes. The scope of the invention encompasses novel compositions and methods of treating demineralized tissues.