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METHODS FOR PREVENTING AND TREATING PNEUMOCYSTIS INFECTIONS

机译：预防和治疗肺脓毒感染的方法

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摘要

The disclosure relates to methods of prophylactic and therapeutic treatments of a Pneumocystis infection (i.e., an infection caused by Pneumocystis jirovecii) in a subject by administering to the subject a compound of any of formulas (1)-(111) (e.g., a salt of Compound 1, or a neutral form thereof). The disclosure also relates to methods of inhibiting the replication of a Pneumocystis spp. The methods of the disclosure can be useful in immunocompromised subjects.

机译：本公开涉及通过向受试者施用任何一种化合物来预防和治疗受试者中的肺孢子虫感染（即，由肺孢子虫jirovecii 引起的感染）的方法。式（1）-（111）的化合物（例如化合物1的盐或其中性形式）。本公开还涉及抑制
肺孢子虫 spp复制的方法。本公开的方法可用于免疫受损的受试者。展开▼

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公开/公告号US2019000917A1

专利类型

公开/公告日2019-01-03

原文格式PDF

申请/专利权人 CIDARA THERAPEUTICS INC.;
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申请/专利号US201716067713

发明设计人 KENNETH BARTIZAL;PAUL DARUWALA;VOON ONG;MAUREEN RODEN;TAYLOR SANDISON;DIRK THYE;
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申请日2017-01-06

分类号A61K38/12;A61K9;A61K45/06;A61P31/10;

国家 US

入库时间 2022-08-21 12:07:13

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机译：向患者静脉内给药的药物组合物及其生产方法，用于治疗和/或预防哺乳动物的真菌感染以及治疗由假丝酵母菌和卡氏肺孢子菌引起的感染

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1. Preventing Implant Bacterial Infections with Interconnected 3D Porous Structures (I3D)— A Proof-of-Concept Study [J] . Steven Guo, Alexandria Ramos, Zhongqiang Li, 生物科学与医学（英文） . 2021,第001期

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