SELECTIVE KILLING OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES

摘要

A method for killing hematopoietic and/or lymphoid tissue cancer cells is provided. The method includes a step identifying a subject having hematopoietic and/or lymphoid tissue cancer with circulating cells or DNA containing elevated levels of uracils and AP sites. The hematopoietic and/or lymphoid tissue cancer cells are contacted (i.e., treated) with an alkoxyamino compound having formula I:; ;wherein:;E is; ;R₁, R₂, R₃, R₄, R₅ are each independently hydrogen (H), C_1-6 alkyl, F, Cl, or Br; and n is 1 to 5.