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WIRELESS OPTOFLUIDIC SYSTEMS FOR PROGRAMMABLE IN VIVO PHARMACOLOGY AND OPTOGENETICS
WIRELESS OPTOFLUIDIC SYSTEMS FOR PROGRAMMABLE IN VIVO PHARMACOLOGY AND OPTOGENETICS
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机译:可在体内药理学和光遗传学中编程的无线光流体系统
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摘要
Provided are implantable, injectable and/or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate, one or more microfluidic channels embedded in or supported by the substrate and a fluid actuator in operational communication with one or more reservoirs and responsive to a wireless control signal. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In some embodiments, the devices are self-powered and fully implantable. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue.
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