Vector recombinant HVT expressing multiple Bird pathogen antigens and their uses

摘要

Claim 1: or a vaccine composition which comprises one or more vectors recombinant herpesvirus of Turkeys (HVT) comprising at least one or more heterólog polynucleotidesOs encoding at least an Antigen from a pathogen Avian.Claim 2: the composition or vaccine of claim 1, wherein the Vector HVT includes: 1) two heterologous polynucleotide.And where the first polinucleótido comprises a polinucleótido that encodes a polypeptide selected from the group consisting of an Antigen VP2 of Infectious Bursal disease virus (IBDVAntigen), a glycoprotein D (GD) of Infectious laryngotracheitis virus (iltv) and a f Antigen of Newcastle Disease Virus (NDV) (f)And where the second polinucleótido comprises a polinucleótido that encodes a polypeptide selected from the group consisting of an Antigen VP2 of Infectious Bursal disease virus (IBDV)Antigen glycoprotein D (GD) of Infectious laryngotracheitis virus (iltv) and a f Antigen of Newcastle Disease Virus (NDV) (f); or 2) a polinucleótido heterologous that codifICA a polypeptide selected from the group consisting of an Antigen VP2 of Infectious Bursal disease virus (IBDV)Antigen glycoprotein D (GD) of Infectious laryngotracheitis virus (iltv) and a f Antigen of Newcastle Disease Virus (NDV)