isolated multispecific antibody construct, nucleic acid sequence, vector, host cell, process for producing antibody construct, pharmaceutical composition, use of antibody construct and kit

摘要

Summary "cd3 and cdh19 antibody constructs" The present invention provides an antibody construct comprising a first human binding domain capable of binding to human cdh19 on the surface of a target cell and a second domain capable of binding to human cd3. on the surface of a t cell. furthermore, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. further, the invention relates to a process for producing the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.