Magnetic nanoparticles decorated with molecules with complementary roles, kit reagents for diagnosis, therapy and teragnóstica of cancer and its use.Radiomarcadas nanoparticles for diagnosis or therapy and its use

摘要

The present invention relates to the magnetic nanoparticles decorated with molecules with additional functions such as recognition and vectorization, preferably.Aptâmero anti MUC1 and monoclonal antibody trastuzumab, in addition to molecules such as diethylenetriaminepentaacetic acid (DTPA), triamina pentaacético acid 1,4,7,10 tetraazacyclododecane - 1,4,7,10 - tetraacético (dota) and ethylene diamine tetraacético acid (EDTA).With the ability to connect contrast agents for diagnosis such as the radioisotope technetium-99m and gallium 68; agents and radiotherapy treatment such as cobalt - 60 and iodine - 131.In addition, the invention relates to a diagnostic kit comprising said nanoparticles for diagnosis or treatment of cancer.