RAS / CAMP / PKA SIGNALING ROUTE REGULATION IN Yeast

摘要

This report refers to modulation in the ras / camp / pka signaling signaling pathway to maintain propagation efficiency and increase yeast cell fermentation efficiency. This report provides yeast cells displaying or engineered to display a modulation in signaling on a ras / camp / pka route, depending on conditions. for example, yeast cells may be selected or genetically engineered to express a mutated ras1 protein, mutated ras2 protein, mutated ira1 protein and / or mutated ira2 protein, optionally in combination with specific promoters. Methods are also provided for the propagation of yeast cells as well as the use of yeast cells to generate a fermented product (such as ethanol).