pharmaceutical composition and combination for treating and / or preventing cancer, antibody or fragment thereof and method for treating and / or preventing cancer

摘要

It is an object of the present invention to identify cancer antigenic proteins specifically expressed on the surface of cancer cells and to provide the use of antibodies directed to such proteins as cancer therapeutic and / or preventive agents. The present invention relates, for example, to a pharmaceutical composition for the treatment and / or prevention of a cancer comprising as an active ingredient an antibody or fragment thereof having immunological reactivity to a mcemp1 protein having the amino acid sequence shown. either in an even numbered sequence: 2 to 8 or an amino acid sequence having 80% or more sequence identity to such amino acid sequences, or to a mcemp1 protein fragment comprising 7 or more consecutive amino acids.