首页> 外国专利> Tissue occlusion agent, related hemostatic, preventive and occlusion or sclerotherapy agents, and mucosal tissue infusion

Tissue occlusion agent, related hemostatic, preventive and occlusion or sclerotherapy agents, and mucosal tissue infusion

机译:组织阻塞剂,相关的止血剂,预防性阻塞剂或硬化剂以及粘膜组织输注

摘要

tissue occlusion agent, related hemostatic, preventive and occlusion or sclerotherapy agents, and mucosal tissue infusion The present invention relates to a bioabsorbable peptide tissue occlusion agent that can be applied to most mammals, including humans , the peptide tissue occlusion agent being obtained by artificial synthesis to prevent virus infection problems and the like. the tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having from 8 to 200 amino acid residues with hydrophilic amino acids and hydrophobic alternately linked amino acids, and is a self-assembling peptide exhibiting a ß structure in an aqueous solution. in the presence of physiological ph and / or a cation.
机译:组织闭塞剂,相关的止血,预防和闭塞或硬化治疗剂以及粘膜组织输注技术领域本发明涉及一种可生物吸收的肽组织闭塞剂,其可以应用于包括人在内的大多数哺乳动物,该肽组织闭塞剂是通过人工合成获得的。以防止病毒感染等问题。组织阻塞剂包含肽,其中该肽是具有8至200个氨基酸残基且具有亲水性氨基酸和疏水性交替连接的氨基酸的两亲性肽,并且是在水溶液中具有β结构的自组装肽。在生理ph和/或阳离子存在下。

著录项

  • 公开/公告号BRPI0920030B1

    专利类型

  • 公开/公告日2019-03-26

    原文格式PDF

  • 申请/专利权人 3-D MATRIX LTD.;

    申请/专利号BR2009PI20030

  • 申请日2009-10-06

  • 分类号A61K38;A61L17;A61L31;A61P7/04;

  • 国家 BR

  • 入库时间 2022-08-21 12:03:02

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