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RESPONSIBILITY BASED ON THE 2,3 DIOXING OF INDUSTRY

机译:基于行业2,3氧化的责任

摘要

This invention relates to the field of cancer prevention and treatment. Specifically,Indoleamine 2,3 -dioxygenase (IDO) protein or peptide fractions thereof, capable of causing anticancer immune responses, is supplied. Specifically,the invention relates to the use of the IDO or peptides derived from it or specific to the IDO T cells for the treatment of cancer. Therefore,the invention relates to an anticancer vaccine which may be used voluntarily in combination with other immunotherapy and specifically for the IDO Tariff T imported or importedIn vivo vaccination as a treatment for cancer. One aspect of the invention is that the medicines provided in the present can be used in combination with cancer chemotherapy. One perfurther aspect relates to the prevention and treatment of infections in the same ways as described above. The use of IDO and its immune peptide fragments in therapy is also provided.the diagnosis and prognosis of cancer and infections.
机译:本发明涉及癌症预防和治疗领域。具体地,提供了能够引起抗癌免疫应答的吲哚胺2,3-二加氧酶(IDO)蛋白或其肽级分。具体而言,本发明涉及IDO或由其衍生或对IDO T细胞特异的肽在治疗癌症中的用途。因此,本发明涉及一种抗癌疫苗,其可以自愿与其他免疫疗法结合使用,并且特别用于进口或进口的体内IDO Tariff T疫苗的注射,以治疗癌症。本发明的一方面是本发明提供的药物可以与癌症化学疗法联合使用。另一个方面涉及以与上述相同的方式预防和治疗感染。还提供了IDO及其免疫肽片段在治疗中的用途。癌症和感染的诊断和预后。

著录项

  • 公开/公告号CY1120352T1

    专利类型

  • 公开/公告日2019-07-10

    原文格式PDF

  • 申请/专利权人 IO BIOTECH APS;

    申请/专利号CY20181100171T

  • 发明设计人 ANDERSEN MADS HALD;STRATEN PER THOR;

    申请日2018-02-12

  • 分类号A61K38/17;A61K38/08;A61K38/10;A61K38/19;A61K38/20;A61K38/44;A61K39;A61K45/06;C12N9/02;

  • 国家 CY

  • 入库时间 2022-08-21 12:02:48

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