;or a pharmaceutically acceptable salt thereof; in combination with an effective amount of an anti-N3pGlu Aβ monoclonal antibody. Moreover, the present invention provides a kit for treating Alzheimer's disease, comprising said compound and monoclonal antibody, as well as the use thereof for treating the mentioned disease."/> COMBINATION ALZHEIMER'S DISEASE THERAPY USING A COMBINATION OF ANTI-N3pGlu Aβ MONOCLONAL ANTIBODIES AND A BACE INHIBITOR
首页> 外国专利> COMBINATION ALZHEIMER'S DISEASE THERAPY USING A COMBINATION OF ANTI-N3pGlu Aβ MONOCLONAL ANTIBODIES AND A BACE INHIBITOR

COMBINATION ALZHEIMER'S DISEASE THERAPY USING A COMBINATION OF ANTI-N3pGlu Aβ MONOCLONAL ANTIBODIES AND A BACE INHIBITOR

机译:抗N3pGluAβ单克隆抗体和抑菌剂联合治疗老年痴呆症

摘要

The present invention provides a method of treating Alzheimer's disease in a patient, comprising administering to a patient in need of such treatment an effective amount of a compound of the formula; ;or a pharmaceutically acceptable salt thereof; in combination with an effective amount of an anti-N3pGlu Aβ monoclonal antibody. Moreover, the present invention provides a kit for treating Alzheimer's disease, comprising said compound and monoclonal antibody, as well as the use thereof for treating the mentioned disease.
机译:本发明提供了一种治疗患者阿尔茨海默氏病的方法,该方法包括向需要这种治疗的患者施用有效量的下式化合物: <图像文件=“ IMGA0002.GIF” he =“ 28” imgContent =“绘图” imgFormat =“ GIF” wi =“ 48” /> ;或其药学上可接受的盐;与有效量的抗N3pGluAβ单克隆抗体联合使用。此外,本发明提供了一种用于治疗阿尔茨海默氏病的试剂盒,其包含所述化合物和单克隆抗体,以及其在治疗所述疾病中的用途。

著录项

  • 公开/公告号EA031764B1

    专利类型

  • 公开/公告日2019-02-28

    原文格式PDF

  • 申请/专利权人 ELI LILLY AND COMPANY;

    申请/专利号EA20170090305

  • 发明设计人 PATRICK CORNELIOUS;DUSTIN JAMES;

    申请日2015-09-08

  • 分类号A61K31/542;C07D513/04;C07K16/18;A61K39/395;

  • 国家 EA

  • 入库时间 2022-08-21 12:02:31

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号