PERSONALIZED IMMUNOTHERAPY OF SEVERAL SPECIES OF NEURAL TUMORS AND BRAIN TUMORS

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated cytotoxic peptide T-cell epitopes (CTLs), alone or in combination with other tumor-associated peptides, which serve as active pharmaceutical ingredients of vaccine compositions that stimulate antitumor immune responses. The present invention relates to peptide sequences and their variants formed from HLA molecules of classes I and II of human tumor cells that can be used in vaccine compositions to elicit antitumor immune responses.