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SAMIDORPHAN (ALKS 33) IN COMBINATION WITH BUPRENORPHINE FOR THE TREATMENT OF DEPRESSIVE DISORDERS
SAMIDORPHAN (ALKS 33) IN COMBINATION WITH BUPRENORPHINE FOR THE TREATMENT OF DEPRESSIVE DISORDERS
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机译：沙米多芬（ALKS 33）联合布伦吗啡治疗抑郁症
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摘要
The invention relates to a composition comprising buprenorphine and a µ opioid receptor antagonist, wherein the composition is characterized by an Agonist Antagonist Activity Index (AAnAI) of between about 0.7 and about 2.2; wherein; AAnAI = / EC 50 c max BUP c max ANTAGONIST / IC 50 .
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机译：本发明涉及一种包含丁丙诺啡和μ阿片样物质受体拮抗剂的组合物，其中该组合物的特征在于激动剂拮抗活性指数（AAnAI）为约0.7至约2.2。其中; AAnAI = / EC 50 c最大BUP c max ANTAGONIST / IC 50。
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