Drugs intermediates o-aminobenzoic acid synthesis method, comprises the following steps: adding 3 mol benzamide in the reaction vessel, reducing the temperature of the solution to 5-10 °C, controlling the stirring speed at 110-130 rpm, adding 4-5 mol 2-methyl phenol, 6 mol oxalic acid solution, the temperature was increased to 20-25°C for 90-130 min, 30g aluminum trichloride powder was added, the solution temperature was increased to 50-55°C, reacted for 30-40 min, 2 L sodium chloride solution was added, the temperature was lowered to 10-15°C, precipitated white crystals, filter it, washed with cyclohexane solution, washed with isopropyl alcohol solution, dehydrated with dehydrating agent, drying at 60-65°C, finally got o-aminobenzoic acid product anthranilic acid.
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